This is a more specialist product, and I’ll be straight with you, it’s not for everyone.

Where it does have relevance is for people who are putting their body under higher levels of stress, particularly enhanced athletes, where cardiovascular health, blood viscosity, and circulation become more important considerations.

Used properly, this sits in that category of supplements that support the systems you don’t feel day-to-day, but matter long-term.

 

Who it’s for:

 

Individuals looking to support circulation, vascular health and blood flow.

Enhanced athletes who are mindful of cardiovascular strain and blood thickness.

Those building a more advanced health stack beyond the basics.

 

What it does:

 

Combines nattokinase and serrapeptase, enzymes often associated with supporting fibrin breakdown and circulation.

Includes French Pine Bark Extract (Pycnogenol®), linked to endothelial function and nitric oxide support.

Adds 1-Octacosanol, often used in cardiovascular and endurance-focused formulas.

 

How I’d use it:

 

Take 1 capsule daily on waking, ideally on an empty stomach.

This is a support product, not a fix — it works alongside good habits, not instead of them.

If you’re enhanced, this becomes part of a wider approach that should include blood work, monitoring, hydration, and sensible decision making.

If you’re on medication (especially blood thinners), speak to your GP before using.

 

The Science:

 

Effects of nattokinase on blood pressure: a randomised, controlled trial

 

Study: Randomised, double-blind, placebo-controlled trial in subjects with pre-hypertension or stage 1 hypertension, assessing nattokinase supplementation on cardiovascular markers.

 

Hypertension Research, 2008

 

https://pubmed.ncbi.nlm.nih.gov/18971533

 

Nattokinase significantly reduced both systolic and diastolic blood pressure, supporting its role in improving circulatory health and vascular function.

 

 

Pycnogenol improves endothelial function in hypertensive patients

 

Study: Double-blind, placebo-controlled clinical trial investigating the effects of French pine bark extract (Pycnogenol®) on vascular function.

 

Life Sciences, 2004

 

https://pubmed.ncbi.nlm.nih.gov/14659974/

 

Pycnogenol® improved endothelial function and blood flow, supporting its use in supplements targeting cardiovascular and circulatory support.